PF3D7_0419900 phosphatidylinositol 4-kinase, putative

PfPI4KIIIB inhibitors reduce protein secretion and export in P. falciparum. Fluorescence microscopy images of parasite infected RBCs treated with the brefeldin A (5μg/mL), torin 2 (10 nM), M-797(4.8μM), OGHL250 (3.1μM), WEHI-518 (200 nM), C3 (1.2 μM), and KDU731 (300 nM) (B). The cells were probed with rabbit anti-Nluc and an EXP2 mouse monoclonal to locate the Hyp1-Nluc reporter protein and the PVM, respectively. Nuclei were stained with DAPI, and the space bar indicates 4μm.

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