Immunoelectron microscopy was performed using affinity-purified anti-PfCRT antibodies. Representative micrographs are shown for each parasite line. Bars correspond to 0.25 mm. Arrowheads indicate immunogold-labeled PfCRT deposits on the digestive vacuole membrane (dvm). DV, digestive vacuole; E, erythrocyte; Hz, hemozoin; P, parasite; ppm, parasite plasma membrane.

Waller KL, Muhle RA, Ursos LM, Horrocks P, Verdier-Pinard D, Sidhu AB, Fujioka H, Roepe PD, Fidock DA. Chloroquine resistance modulated in vitro by expression levels of the Plasmodium falciparum chloroquine resistance transporter. J Biol Chem. 2003 278:33593-601.