Malaria Parasite Metabolic Pathways
Drugs affecting pathway with unknown specific target
| Drug Name | PubMed Articles (year of publication) |
|---|---|
| 3,5-dithiocyanatopyridine-2,6-diamine; |
General roles of deubiquitinases map details
| PFID | PFID Old | Annotation | Formal Annotation | EC | Transcript |
|---|---|---|---|---|---|
PF3D7_0104300
|
PFA0220w | DUB | ubiquitin carboxyl-terminal hydrolase 1, putative | 3.4.19.12 |
|
| PF3D7_0413900 | PFD0680c | DUB | ubiquitin carboxyl-terminal hydrolase 13, putative | 3.4.19.12 |
|
| PF3D7_0516700 | PFE0835w | DUB | ubiquitin carboxyl-terminal hydrolase 2, putative | 3.4.19.12 |
|
|
PF3D7_0527200
|
PFE1355c | DUB | ubiquitin carboxyl-terminal hydrolase 14 | 3.4.19.12 |
|
| PF3D7_0630600 | PFF1485w | DUB | deubiquitinating enzyme mindy, putative |
|
|
| PF3D7_0722300 | MAL7P1.120 | DUB | ubiquitin carboxyl-terminal hydrolase, putative | 3.4.19.12 |
|
| PF3D7_0726500 | MAL7P1.147 | DUB | ubiquitin carboxyl-terminal hydrolase, putative | 3.4.19.12 |
|
| PF3D7_1117100 | PF11_0177 | DUB | ubiquitin carboxyl-terminal hydrolase uch54 | 3.4.19.12 |
|
| PF3D7_1414700 | PF14_0145 | DUB | ubiquitin carboxyl-terminal hydrolase, putative | 3.4.19.12 |
|
|
PF3D7_1460400
|
PF14_0576 | DUB | ubiquitin carboxyl-terminal hydrolase isozyme L3 | 3.4.19.12 |
|
|
PF3D7_0312100
|
PFC0510w | E3 | E3 ubiquitin-protein ligase, putative | 6.3.2.19 |
|
|
PF3D7_0316900
|
PFC0740c | E3 | E3 ubiquitin-protein ligase, putative | 6.3.2.19 |
|
| PF3D7_0319100 | PFC0845c | E3 | E3 ubiquitin-protein ligase RBX1, putative | 6.3.2.19 |
|
| PF3D7_0627300 | PFF1325c | E3 | E3 ubiquitin-protein ligase RNF5, putative | 6.3.2.19 |
|
|
PF3D7_0628100
|
PFF1365c | E3 | hect domain-containing protein 1, putative | 6.3.2.19 |
|
|
PF3D7_0704600
|
MAL7P1.19 | E3 | HECT-type E3 ubiquitin ligase UT | 2.3.2.26 |
|
| PF3D7_0707700 | PF07_0026 | E3 | E3 ubiquitin-protein ligase, putative | 6.3.2.19 |
|
| PF3D7_1119400 | PF11_0201 | E3 | ubiquitin-protein ligase, putative | 6.3.2.19 |
|
| PF3D7_0826100 | MAL8P1.23 | HECT-like E3 ubiquitin ligase, putative | HECT-like E3 ubiquitin ligase, putative | 6.3.2.19 |
|
| PF3D7_1211800 | PFL0585w | polyubiquitin | polyubiquitin |
|
|
| PF3D7_1402500 | PF14_0027 | ribosomal protein s27a, putative | ribosomal protein s27a, putative |
|
|
|
PF3D7_0815700
|
PF08_0067 | ubiquitin | apicoplast ubiquitin-like protein aubl |
|
|
|
PF3D7_0922100
|
PFI1085w | ubiquitin | ubiquitin-like protein, putative |
|
|
| PF3D7_1132000 | PF11_0329 | ubiquitin | ubiquitin-like protein, putative |
|
|
|
PF3D7_1314800
|
PF13_0084 | ubiquitin | ubiquitin-like protein, putative |
|
|
|
PF3D7_1365900
|
PF13_0346 | ubiquitin-60S ribosomal protein L40 | ubiquitin-60S ribosomal protein L40 |
|
Total number of related proteins: 10
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFA0220w
|
ubiquitin carboxyl-terminal hydrolase 1, putative |
| 2 | PFD0680c | ubiquitin carboxyl-terminal hydrolase 13, putative |
| 3 | PFE0835w | ubiquitin carboxyl-terminal hydrolase 2, putative |
| 4 |
PFE1355c
|
ubiquitin carboxyl-terminal hydrolase 14 |
| 5 | PFF1485w | deubiquitinating enzyme mindy, putative |
| 6 | MAL7P1.120 | ubiquitin carboxyl-terminal hydrolase, putative |
| 7 | MAL7P1.147 | ubiquitin carboxyl-terminal hydrolase, putative |
| 8 | PF11_0177 | ubiquitin carboxyl-terminal hydrolase uch54 |
| 9 | PF14_0145 | ubiquitin carboxyl-terminal hydrolase, putative |
| 10 |
PF14_0576
|
ubiquitin carboxyl-terminal hydrolase isozyme L3 |
Total number of related proteins: 8
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFC0510w
|
E3 ubiquitin-protein ligase, putative |
| 2 |
PFC0740c
|
E3 ubiquitin-protein ligase, putative |
| 3 | PFC0845c | E3 ubiquitin-protein ligase RBX1, putative |
| 4 | PFF1325c | E3 ubiquitin-protein ligase RNF5, putative |
| 5 |
PFF1365c
|
hect domain-containing protein 1, putative |
| 6 |
MAL7P1.19
|
HECT-type E3 ubiquitin ligase UT |
| 7 | PF07_0026 | E3 ubiquitin-protein ligase, putative |
| 8 | PF11_0201 | ubiquitin-protein ligase, putative |
Total number of related proteins: 4
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF08_0067
|
apicoplast ubiquitin-like protein aubl |
| 2 |
PFI1085w
|
ubiquitin-like protein, putative |
| 3 | PF11_0329 | ubiquitin-like protein, putative |
| 4 |
PF13_0084
|
ubiquitin-like protein, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | MAL8P1.23 | HECT-like E3 ubiquitin ligase, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFL0585w | polyubiquitin |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF13_0346
|
ubiquitin-60S ribosomal protein L40 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF14_0027 | ribosomal protein s27a, putative |