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Localization and function of some Hsp40s and Hsp70s |
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Pesce ER, Blatch GL. Plasmodial Hsp40 and Hsp70 chaperones: current and future perspectives. Parasitology. 2014 25:1-10. PMID: 24666996. |
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Name |
PfID |
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Localization |
Function |
Transcript |
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| 25706 |
Pfj1 |
PF3D7_0409400 |
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chaperone protein dnaj; heat shock protein 40 |
Apicoplast genome replication, interaction with Hsp70-1? |
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| 23915 |
Hsp40 |
PF3D7_1437900 |
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HSP40, subfamily A |
Protein folding? Associates with Hsp70-1 |
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| 12193 |
Pfj2 |
PF3D7_1108700 |
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heat shock protein 40, type ii |
Chaperoning of exported proteins withHsp70-x? |
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| 12197 |
Pfj4 |
PF3D7_1211400 |
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heat shock protein DNAJ homologue Pfj4 |
Chaperoning of knob components? |
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| 12182 |
HSP40 |
PF3D7_0113700 |
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heat shock protein 40, type II |
Chaperoning of exported proteins withHsp70-x? |
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| 12183 |
KAHsp40 |
PF3D7_0201800 |
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knob associated heat shock protein 40 |
Translocation of nascent proteins into the ER? Interaction with PfBiP? |
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| 12186 |
HSP40 |
PF3D7_0501100 |
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co-chaperone j domain protein jdp |
Binding to 4.1 protein |
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| 12199 |
Sec63 |
PF3D7_1318800 |
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translocation protein SEC63 |
Gametocyte sequestration? |
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| 12185 |
MESA/PfEMP2 |
PF3D7_0500800 |
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erythrocyte membrane protein 2 mature parasite-infected erythrocyte surface antigen |
Interaction with spectrin, cytoskeleton thermal stability |
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| 12198 |
PfGECO |
PF3D7_1253000 |
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gametocyte exported protein 1 gametocyte erythrocyte cytosolic protein |
Unknown |
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| 12181 |
RESA |
PF3D7_0102200 |
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ring-infected erythrocyte surface antigen |
Unknown |
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| 12196 |
RESA2 |
PF3D7_1149500 |
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ring-infected erythrocyte surface antigen 2, pseudogene |
Knob formation |
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| 12195 |
RESA3 |
PF3D7_1149200 |
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ring-infected erythrocyte surface antigen |
Protein folding associated with Pfj4, Hsp40? And Pfj1? |
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| 12192 |
DnaJ |
PF3D7_1039100 |
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DnaJ protein, putative, pseudogene? MEC domain-containing protein |
Protein folding in the ER? |
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| 12188 |
Hsp70-1 |
PF3D7_0818900 |
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PfHsp70-1 |
Unknown |
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| 12190 |
Hsp70-2/BiP |
PF3D7_0917900 |
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PfHsp70-2 |
Chaperoning of exported proteins with PFE0055c and PFA0660w? Chaperoning of exported proteins in the PV? |
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| 12194 |
Hsp70-3 |
PF3D7_1134000 |
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PfHsp70-3 |
NEF? |
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| 12189 |
Hsp70-x |
PF3D7_0831700 |
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PfHsp70-x |
Prevention of protein aggregation; NEF? |
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| 12200 |
Hsp70-y |
PF3D7_1344200 |
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PfHsp70-y |
NEF? |
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| 12187 |
Hsp70-z/Hsp110c |
PF3D7_0708800 |
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PfHsp70-z |
Prevention of protein aggregation; NEF? |
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NEF=nucleotide exchange factor |
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