| Important interacting proteins |
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| Bhattacharyya M, Chakrabarti S. Identification of important interacting proteins (IIPs) in Plasmodium falciparum using large-scale interaction network analysis and in-silico knock-out studies. Malar J. 2015 Feb 8;14:70 |
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| Shown are the expression pattern of interacting partners (protein 1 & protein 2) and the expression of both proteins in 4 intraerythrocytic stages: merozoite (M), ring stage(R), trophozoite (T), and schizont (S). Each stage is denoted by a color. Hence a box is colored if the protein is present in that stage and the box is white if it is absent. At least one partner of the interaction is present in any one stage only. Hence the interaction cannot happen in other stages even if the other partner is present in other stages. That is why when you look at the ring stage specific file you will see any one of the protein 1 or proein 2 is expressed uniquely in ring stage and the other one could be present in other stages also. This observation basically indicates a dynamic pattern of interaction in which a single protein interacts with different proteins in different stages. The colored PfIDs are important interacting proteins (see original article) |
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| Stage-specific interactions by IIPs in Ring stage |
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| Protein 1 |
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Protein Name |
M |
R |
T |
S |
EC# |
Protein 2 |
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Protein Name |
M |
R |
T |
S |
EC# |
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| PF3D7_0708100 |
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DNA-directed RNA polymerases I, II, and III subunit RPABC5, putative |
S |
S |
S |
S |
2.7.7.6 |
PF3D7_1329000 |
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DNA-directed RNA polymerase III subunit RPC1, putative |
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S |
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2.7.7.6 |
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| PF3D7_1023900 |
 |
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SNF2 helicase, putative chromodomain-helicase-DNA-binding protein 1 homolog, putative |
S |
S |
S |
S |
3.6.4.12 |
PF3D7_1138700 |
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conserved Plasmodium protein, unknown function |
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S |
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| PF3D7_1125500 |
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small nuclear ribonucleoprotein Sm D1, putative |
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S |
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PF3D7_1325000 |
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U6 snRNA-associated Sm-like protein LSm6, putative |
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S |
S |
S |
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| PF3D7_1329000 |
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DNA-directed RNA polymerase III subunit RPC1, putative |
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S |
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2.7.7.6 |
PF3D7_1364800 |
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DNA-directed RNA polymerases I, II, and III subunit RPABC1, putative |
S |
S |
S |
S |
2.7.7.6 |
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| PF3D7_1329000 |
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DNA-directed RNA polymerase III subunit RPC1, putative |
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S |
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2.7.7.6 |
PF3D7_1415200 |
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DNA-directed RNA polymerases I and III subunit RPAC2, putative |
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S |
S |
S |
2.7.7.6 |
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| PF3D7_1329000 |
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DNA-directed RNA polymerase III subunit RPC1, putative |
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S |
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2.7.7.6 |
PF3D7_1213700 |
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DNA-directed RNA polymerases I, II, and III subunit RPABC3, putative |
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S |
S |
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2.7.7.6 |
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| PF3D7_1410200 |
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cytidine triphosphate synthetase |
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S |
S |
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6.3.4.2 |
PF3D7_0102500 |
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erythrocyte binding antigen-181 |
S |
S |
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S |
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| PF3D7_1434500 |
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dynein-related AAA-type ATPase, putative |
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S |
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3.6.4.2 |
PF3D7_1105400 |
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40S ribosomal protein S4, putative |
S |
S |
S |
S |
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| PF3D7_1434500 |
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dynein-related AAA-type ATPase, putative |
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S |
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3.6.4.2 |
PF3D7_1327800 |
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ribose-phosphate pyrophosphokinase, putative |
S |
S |
S |
S |
2.7.6.1 |
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| PF3D7_1434500 |
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dynein-related AAA-type ATPase, putative |
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S |
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3.6.4.2 |
PF3D7_0405400 |
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pre-mRNA-processing-splicing factor 8, putative |
S |
S |
S |
S |
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| PF3D7_1434500 |
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dynein-related AAA-type ATPase, putative |
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S |
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3.6.4.2 |
PF3D7_0511000 |
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translationally-controlled tumor protein homolog |
S |
S |
S |
S |
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| PF3D7_1466900 |
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rhoptry protein, putative |
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S |
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PF3D7_1236100 |
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clustered-asparagine-rich protein |
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S |
S |
S |
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| PF3D7_0206800 |
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merozoite surface protein 2 |
S |
S |
S |
S |
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PF3D7_1138700 |
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conserved Plasmodium protein, unknown function |
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S |
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| PF3D7_0303300 |
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DNA-directed RNA polymerases I, II, and III subunit RPABC2, putative |
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S |
S |
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2.7.7.6 |
PF3D7_0830500 |
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tryptophan/threonine-rich antigen sporozoite and liver stage tryptophan-rich protein, putative |
S |
S |
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| PF3D7_0500800 |
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erythrocyte membrane protein 2 mature parasite-infected erythrocyte surface antigen |
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S |
S |
S |
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PF3D7_1434500 |
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dynein-related AAA-type ATPase, putative |
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S |
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3.6.4.2 |
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| PF3D7_0518300 |
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proteasome subunit beta type-1, putative |
S |
S |
S |
S |
3.4.25.1 |
PF3D7_0918900 |
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gamma-glutamylcysteine synthetase |
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S |
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6.3.2.2 |
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| PF3D7_0919900 |
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regulator of chromosome condensation, putative |
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S |
S |
S |
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PF3D7_0830500 |
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tryptophan/threonine-rich antigen sporozoite and liver stage tryptophan-rich protein, putative |
S |
S |
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| Stage-specific interactions by IIPs in Trophozoite stage |
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| Protein 1 |
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Protein Name |
M |
R |
T |
S |
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Protein 2 |
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Protein Name |
M |
R |
T |
S |
EC# |
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| PF3D7_1368200 |
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ABC transporter E family member 1, putative |
S |
S |
S |
S |
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PF3D7_0919700 |
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pyridoxal 5'-phosphate dependent enzyme class III, putative |
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S |
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5.1.1.1 |
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| PF3D7_1317800 |
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40S ribosomal protein S19 |
S |
S |
S |
S |
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PF3D7_0412100 |
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mitochondrial ribosomal protein S12 precursor, putative |
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S |
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| PF3D7_0718400 |
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mitochondrial ribosomal protein S8 precursor, putative |
S |
S |
S |
S |
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PF3D7_0412100 |
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mitochondrial ribosomal protein S12 precursor, putative |
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S |
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| PF3D7_0721600 |
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40S ribosomal protein S5, putative |
S |
S |
S |
S |
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PF3D7_0412100 |
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mitochondrial ribosomal protein S12 precursor, putative |
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S |
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| PF3D7_0823300 |
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histone acetyltransferase GCN5 |
S |
S |
S |
S |
2.3.1.48 |
PF3D7_1475000 |
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mediator of RNA polymerase ii transcription subunit 31, putative |
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S |
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| PF3D7_0813900 |
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40S ribosomal protein S16, putative |
S |
S |
S |
S |
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PF3D7_0412100 |
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mitochondrial ribosomal protein S12 precursor, putative |
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S |
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| PF3D7_1022800 |
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4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase |
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S |
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1.17.7.1 |
PF3D7_0405400 |
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pre-mRNA-processing-splicing factor 8, putative |
S |
S |
S |
S |
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| PF3D7_1026800 |
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40S ribosomal protein S2 |
S |
S |
S |
S |
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PF3D7_0412100 |
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mitochondrial ribosomal protein S12 precursor, putative |
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S |
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| PF3D7_1034200 |
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apicoplast ribosomal protein L27 precursor, putative |
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S |
S |
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PF3D7_0212200 |
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mitochondrial ribosomal protein L12 precursor, putative |
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S |
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| PF3D7_1034200 |
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apicoplast ribosomal protein L27 precursor, putative |
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S |
S |
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PF3D7_1233000 |
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elongation factor G |
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S |
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| PF3D7_1102300 |
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Plasmodium exported protein, unknown function |
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S |
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PF3D7_1339700 |
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conserved Plasmodium protein, unknown function |
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S |
S |
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| PF3D7_1107300 |
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polyadenylate-binding protein-interacting protein 1, putative |
S |
S |
S |
S |
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PF3D7_0711400 |
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histone deacetylase complex subunit SAP18, putative |
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S |
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| PF3D7_1110600 |
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mitochondrial ribosomal protein L11 precursor, putative |
S |
S |
S |
S |
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PF3D7_0212200 |
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mitochondrial ribosomal protein L12 precursor, putative |
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S |
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| PF3D7_1110600 |
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mitochondrial ribosomal protein L11 precursor, putative |
S |
S |
S |
S |
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PF3D7_0412100 |
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mitochondrial ribosomal protein S12 precursor, putative |
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S |
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| PF3D7_1110600 |
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mitochondrial ribosomal protein L11 precursor, putative |
S |
S |
S |
S |
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PF3D7_1233000 |
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elongation factor G |
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S |
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| PF3D7_1131200 |
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conserved Plasmodium protein, unknown function |
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S |
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PF3D7_0220000 |
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liver stage antigen 3 |
S |
S |
S |
S |
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| PF3D7_1132700 |
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50s ribosomal protein l2, putative |
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S |
S |
S |
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PF3D7_0212200 |
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mitochondrial ribosomal protein L12 precursor, putative |
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S |
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| PF3D7_1149000 |
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antigen 332, DBL-like protein |
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S |
S |
S |
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PF3D7_1022000 |
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RNA-binding protein, putative |
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S |
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| PF3D7_1333600 |
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U3 small nucleolar RNA-associated protein 4, putative |
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S |
S |
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PF3D7_0410800 |
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conserved Plasmodium protein, unknown function |
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S |
S |
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| PF3D7_1415400 |
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conserved Plasmodium protein, unknown function |
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S |
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PF3D7_1307200 |
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DnaJ protein, putative |
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S |
S |
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| PF3D7_1415400 |
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conserved Plasmodium protein, unknown function |
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S |
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PF3D7_1354300 |
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large subunit rRNA methyltransferase, putative |
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S |
S |
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2.1.1.- |
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| PF3D7_1452400 |
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conserved Plasmodium protein, unknown function |
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S |
S |
S |
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PF3D7_1415400 |
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conserved Plasmodium protein, unknown function |
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S |
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| PF3D7_1464000 |
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YL1 nuclear protein, putative |
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S |
S |
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PF3D7_1448500 |
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conserved Plasmodium protein, unknown function |
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S |
S |
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| PF3D7_1474100 |
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mitochondrial ribosomal protein L20 precursor, putative |
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S |
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PF3D7_0212200 |
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mitochondrial ribosomal protein L12 precursor, putative |
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S |
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| PF3D7_1474100 |
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mitochondrial ribosomal protein L20 precursor, putative |
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S |
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PF3D7_0214200 |
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mitochondrial ribosomal protein L13 precursor, putative |
S |
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S |
S |
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| PF3D7_1474100 |
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mitochondrial ribosomal protein L20 precursor, putative |
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S |
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PF3D7_1223900 |
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50S ribosomal protein L24, putative |
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S |
S |
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| PF3D7_1475000 |
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mediator of RNA polymerase ii transcription subunit 31, putative |
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S |
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PF3D7_0215700 |
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DNA-directed RNA polymerase II subunit RPB2 |
S |
S |
S |
S |
2.7.7.6 |
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| PF3D7_0102600 |
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serine/threonine protein kinase, FIKK family |
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S |
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2.7.11.1 |
PF3D7_0532100 |
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early transcribed membrane protein 5 |
S |
S |
S |
S |
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| PF3D7_0108700 |
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secreted ookinete protein, putative |
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S |
S |
S |
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PF3D7_1468900 |
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conserved Plasmodium protein, unknown function |
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S |
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| PF3D7_0212200 |
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mitochondrial ribosomal protein L12 precursor, putative |
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S |
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PF3D7_0214200 |
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mitochondrial ribosomal protein L13 precursor, putative |
S |
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S |
S |
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| PF3D7_0212200 |
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mitochondrial ribosomal protein L12 precursor, putative |
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S |
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PF3D7_0519100 |
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mitochondrial ribosomal protein L14 precursor, putative |
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S |
S |
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| PF3D7_0214200 |
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mitochondrial ribosomal protein L13 precursor, putative |
S |
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S |
S |
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PF3D7_0412100 |
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mitochondrial ribosomal protein S12 precursor, putative |
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S |
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| PF3D7_0214200 |
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mitochondrial ribosomal protein L13 precursor, putative |
S |
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S |
S |
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PF3D7_1233000 |
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elongation factor G |
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S |
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| PF3D7_0303300 |
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DNA-directed RNA polymerases I, II, and III subunit RPABC2, putative |
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S |
S |
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2.7.7.6 |
PF3D7_1440100 |
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conserved Plasmodium protein, unknown function |
|
|
S |
S |
|
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| PF3D7_0400200 |
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erythrocyte membrane protein 1 (PfEMP1), exon 2, pseudogene |
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|
S |
S |
|
PF3D7_1478600 |
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EMP1-trafficking protein |
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S |
S |
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| PF3D7_0412100 |
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|
mitochondrial ribosomal protein S12 precursor, putative |
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|
S |
|
|
PF3D7_0516200 |
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40S ribosomal protein S11 |
S |
S |
S |
S |
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|
|
|
|
|
|
| PF3D7_0413600 |
|
|
26S protease regulatory subunit 6B, putative; 26S proteasome AAA-ATPase subunit RPT3 |
S |
S |
S |
S |
3.6.4.8 |
PF3D7_0519700 |
|
|
conserved Plasmodium protein, unknown function |
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0519700 |
|
|
conserved Plasmodium protein, unknown function |
|
|
S |
|
|
PF3D7_0919000 |
|
|
nucleosome assembly protein |
S |
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0905900 |
|
|
coatomer subunit beta, putative |
|
S |
S |
S |
|
PF3D7_0724100 |
|
|
conserved Plasmodium protein, unknown function |
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0905900 |
|
|
coatomer subunit beta, putative |
|
S |
S |
S |
|
PF3D7_0519700 |
|
|
conserved Plasmodium protein, unknown function |
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0918200 |
|
|
50S ribosomal protein L3, apicoplast, putative |
S |
S |
S |
S |
|
PF3D7_1233000 |
|
|
elongation factor G |
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0923000 |
|
|
DNA-directed RNA polymerase II subunit RPB3 |
|
|
S |
|
2.7.7.6 |
PF3D7_1213700 |
|
|
DNA-directed RNA polymerases I, II, and III subunit RPABC3, putative |
|
S |
S |
|
2.7.7.6 |
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0936800 |
|
|
Plasmodium exported protein (PHISTc), unknown function |
|
S |
S |
|
|
PF3D7_1036600 |
|
|
conserved Plasmodium protein, unknown function |
|
|
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0936800 |
|
|
Plasmodium exported protein (PHISTc), unknown function |
|
S |
S |
|
|
PF3D7_1116000 |
|
|
rhoptry neck protein 4 |
|
|
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0936800 |
|
|
Plasmodium exported protein (PHISTc), unknown function |
|
S |
S |
|
|
PF3D7_0510100 |
|
|
conserved Plasmodium protein, unknown function |
|
|
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1211800 |
|
|
polyubiquitin |
S |
S |
S |
S |
|
PF3D7_1415400 |
|
|
conserved Plasmodium protein, unknown function |
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Stage-specific interactions by IIPs in Schizont stage |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Protein 1 |
|
|
Protein Name |
M |
R |
T |
S |
|
Protein 2 |
|
|
Protein Name |
M |
R |
T |
S |
EC# |
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1339700 |
|
|
conserved Plasmodium protein, unknown function |
|
|
S |
S |
|
PF3D7_1252400 |
|
|
reticulocyte binding protein homologue 3, pseudogene |
|
S |
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1340900 |
|
|
sodium-dependent phosphate transporter |
S |
S |
S |
S |
|
PF3D7_1335100 |
|
|
merozoite surface protein 7 |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1366900 |
|
|
conserved Plasmodium protein, unknown function |
S |
S |
S |
S |
|
PF3D7_1035700 |
|
|
duffy binding-like merozoite surface protein |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0703600 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
S |
|
PF3D7_0400200 |
|
|
erythrocyte membrane protein 1 (PfEMP1), exon 2, pseudogene |
|
|
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0726500 |
|
|
ubiquitin carboxyl-terminal hydrolase, putative |
|
S |
S |
S |
3.4.19.12 |
PF3D7_1335400 |
|
|
reticulocyte binding protein 2 homologue a |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0702100 |
|
|
Plasmodium exported protein (PHISTb), unknown function, pseudogene |
S |
S |
|
S |
|
PF3D7_1019600 |
|
|
conserved Plasmodium protein, unknown function |
|
|
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0702100 |
|
|
Plasmodium exported protein (PHISTb), unknown function, pseudogene |
S |
S |
|
S |
|
PF3D7_1133200 |
|
|
conserved Plasmodium protein, unknown function |
|
|
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0702100 |
|
|
Plasmodium exported protein (PHISTb), unknown function, pseudogene |
S |
S |
|
S |
|
PF3D7_0207700 |
|
|
serine repeat antigen 4 |
|
|
S |
S |
3.4.22.- |
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0802100 |
|
|
Ap2 domain transcription factor, putative |
|
|
|
S |
|
PF3D7_0532400 |
|
|
lysine-rich membrane-associated PHISTb protein |
|
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0826100 |
|
|
E3 ubiquitin-protein ligase, putative |
|
S |
S |
S |
6.3.2.19 |
PF3D7_0220800 |
|
|
cytoadherence linked asexual protein 2 |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0713900 |
|
|
conserved Plasmodium protein, unknown function |
|
S |
S |
S |
|
PF3D7_0508900 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0715600 |
|
|
GTP-binding translation elongation factor tu family protein, putative |
|
|
S |
S |
|
PF3D7_0202200 |
|
|
EMP1-trafficking protein |
S |
S |
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0716100 |
|
|
protein SDA1, putative |
S |
S |
S |
S |
|
PF3D7_1335400 |
|
|
reticulocyte binding protein 2 homologue a |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0817600 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
S |
|
PF3D7_0801000 |
|
|
Plasmodium exported protein (PHISTc), unknown function |
S |
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0802000 |
|
|
glutamate dehydrogenase, putative |
|
S |
S |
S |
1.4.1.2 |
PF3D7_1335400 |
|
|
reticulocyte binding protein 2 homologue a |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1011400 |
|
|
proteasome subunit beta type-5 |
|
S |
S |
S |
3.4.25.1 |
PF3D7_1035700 |
|
|
duffy binding-like merozoite surface protein |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1030100 |
|
|
pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22, putative |
S |
S |
S |
S |
3.6.4.13 |
PF3D7_1335400 |
|
|
reticulocyte binding protein 2 homologue a |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1033300 |
|
|
conserved Plasmodium protein, unknown function |
|
S |
S |
S |
|
PF3D7_1126700 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1034200 |
|
|
apicoplast ribosomal protein L27 precursor, putative |
|
|
S |
S |
|
PF3D7_1210000 |
|
|
50S ribosomal protein L1, apicoplast, putative |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1035400 |
|
|
merozoite surface protein 3 |
|
|
S |
S |
|
PF3D7_1451700 |
|
|
calcineurin subunit B |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1035700 |
|
|
duffy binding-like merozoite surface protein |
|
|
|
S |
|
PF3D7_1019000 |
|
|
eukaryotic translation initiation factor subunit eIF2A, putative |
S |
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1035700 |
|
|
duffy binding-like merozoite surface protein |
|
|
|
S |
|
PF3D7_1124900 |
|
|
60S ribosomal protein L35, putative |
S |
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1035700 |
|
|
duffy binding-like merozoite surface protein |
|
|
|
S |
|
PF3D7_1441400 |
|
|
FACT complex subunit SSRP1, putative |
|
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1110600 |
|
|
mitochondrial ribosomal protein L11 precursor, putative |
S |
S |
S |
S |
|
PF3D7_1210000 |
|
|
50S ribosomal protein L1, apicoplast, putative |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1112100 |
|
|
conserved Plasmodium protein, unknown function |
|
|
S |
S |
|
PF3D7_1335400 |
|
|
reticulocyte binding protein 2 homologue a |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1126700 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
S |
|
PF3D7_0511500 |
|
|
RNA pseudouridylate synthase, putative |
S |
S |
S |
S |
5.4.99.12 |
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1132700 |
|
|
50s ribosomal protein l2, putative |
|
S |
S |
S |
|
PF3D7_1210000 |
|
|
50S ribosomal protein L1, apicoplast, putative |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1138500 |
|
|
protein phosphatase 2C protein phosphatase PPM2 |
S |
S |
S |
S |
3.1.3.16 |
PF3D7_1335400 |
|
|
reticulocyte binding protein 2 homologue a |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1149000 |
|
|
antigen 332, DBL-like protein |
|
S |
S |
S |
|
PF3D7_0705300 |
|
|
origin recognition complex subunit 2, putative |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1335100 |
|
|
merozoite surface protein 7 |
|
|
|
S |
|
PF3D7_0815800 |
|
|
vacuolar protein sorting-associated protein 9, putative |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1335100 |
|
|
merozoite surface protein 7 |
|
|
|
S |
|
PF3D7_0828800 |
|
|
GPI-anchored micronemal antigen |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1335100 |
|
|
merozoite surface protein 7 |
|
|
|
S |
|
PF3D7_1023900 |
|
|
SNF2 helicase, putative chromodomain-helicase-DNA-binding protein 1 homolog, putative |
S |
S |
S |
S |
3.6.4.12 |
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1335100 |
|
|
merozoite surface protein 7 |
|
|
|
S |
|
PF3D7_1351800 |
|
|
conserved Plasmodium protein, unknown function |
S |
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1335100 |
|
|
merozoite surface protein 7 |
|
|
|
S |
|
PF3D7_1437900 |
|
|
HSP40, subfamily A |
S |
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1335100 |
|
|
merozoite surface protein 7 |
|
|
|
S |
|
PF3D7_1462800 |
|
|
glyceraldehyde-3-phosphate dehydrogenase |
S |
S |
S |
S |
1.2.1.12 |
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1335100 |
|
|
merozoite surface protein 7 |
|
|
|
S |
|
PF3D7_0527500 |
|
|
Hsc70-interacting protein |
S |
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1335100 |
|
|
merozoite surface protein 7 |
|
|
|
S |
|
PF3D7_0907200 |
|
|
GTPase-activating protein, putative |
|
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1335100 |
|
|
merozoite surface protein 7 |
|
|
|
S |
|
PF3D7_1228600 |
|
|
merozoite surface protein 9 |
|
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1335400 |
|
|
reticulocyte binding protein 2 homologue a |
|
|
|
S |
|
PF3D7_1021800 |
|
|
hypothetical protein |
|
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1335400 |
|
|
reticulocyte binding protein 2 homologue a |
|
|
|
S |
|
PF3D7_1452500 |
|
|
SNARE protein, putative |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1335400 |
|
|
reticulocyte binding protein 2 homologue a |
|
|
|
S |
|
PF3D7_0420300 |
|
|
AP2 domain transcription factor |
|
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1420700 |
|
|
surface protein P113 |
S |
S |
S |
S |
|
PF3D7_1335100 |
|
|
merozoite surface protein 7 |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1439500 |
|
|
oocyst rupture protein 2, putative |
S |
S |
|
S |
|
PF3D7_1335100 |
|
|
merozoite surface protein 7 |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1452400 |
|
|
conserved Plasmodium protein, unknown function |
|
S |
S |
S |
|
PF3D7_1313500 |
|
|
conserved Plasmodium membrane protein, unknown function |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1452400 |
|
|
conserved Plasmodium protein, unknown function |
|
S |
S |
S |
|
PF3D7_1463900 |
|
|
conserved Plasmodium membrane protein, unknown function |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_1475600 |
|
|
bromodomain protein, putative |
|
S |
|
S |
|
PF3D7_1335400 |
|
|
reticulocyte binding protein 2 homologue a |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0102500 |
|
|
erythrocyte binding antigen-181 |
S |
S |
|
S |
|
PF3D7_1126700 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0108300 |
|
|
conserved Plasmodium protein, unknown function |
S |
S |
S |
S |
|
PF3D7_1014100 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0108700 |
|
|
secreted ookinete protein, putative |
|
S |
S |
S |
|
PF3D7_1035700 |
|
|
duffy binding-like merozoite surface protein |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0110900 |
|
|
adenylate kinase-like protein 1 |
|
|
|
S |
2.7.4.3 |
PF3D7_0208200 |
|
|
KRR1 small subunit processome component, putative |
S |
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0110900 |
|
|
adenylate kinase-like protein 1 |
|
|
|
S |
2.7.4.3 |
PF3D7_0516200 |
|
|
40S ribosomal protein S11 |
S |
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0202400 |
|
|
gamete antigen 27/25, putative |
|
S |
S |
S |
|
PF3D7_1335100 |
|
|
merozoite surface protein 7 |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0214200 |
|
|
mitochondrial ribosomal protein L13 precursor, putative |
S |
|
S |
S |
|
PF3D7_1210000 |
|
|
50S ribosomal protein L1, apicoplast, putative |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0217100 |
|
|
ATP synthase F1, alpha subunit |
S |
S |
S |
S |
3.6.3.14 |
PF3D7_1210000 |
|
|
50S ribosomal protein L1, apicoplast, putative |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0220800 |
|
|
cytoadherence linked asexual protein 2 |
|
|
|
S |
|
PF3D7_0904600 |
|
|
ubiquitin specific protease, putative |
|
S |
S |
S |
3.4.19.12 |
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0308700 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
S |
|
PF3D7_1003600 |
|
|
inner membrane complex protein 1c, putative |
S |
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0308700 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
S |
|
PF3D7_1021800 |
|
|
hypothetical protein |
|
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0308700 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
S |
|
PF3D7_1325400 |
|
|
conserved Plasmodium protein, unknown function |
|
|
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0308700 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
S |
|
PF3D7_1419000 |
|
|
conserved Plasmodium protein, unknown function |
|
|
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0316500 |
|
|
kinetochore protein NUF2, putative |
|
|
|
S |
|
PF3D7_0930300 |
|
|
merozoite surface protein 1 |
S |
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0400200 |
|
|
erythrocyte membrane protein 1 (PfEMP1), exon 2, pseudogene |
|
|
S |
S |
|
PF3D7_1335400 |
|
|
reticulocyte binding protein 2 homologue a |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0401800 |
|
|
Plasmodium exported protein (PHISTb), unknown function |
|
S |
S |
S |
|
PF3D7_1035300 |
|
|
glutamate-rich protein |
S |
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0404700 |
|
|
dipeptidyl aminopeptidase 3 |
|
|
|
S |
3.4.14.4 |
PF3D7_1035400 |
|
|
merozoite surface protein 3 |
|
|
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0404700 |
|
|
dipeptidyl aminopeptidase 3 |
|
|
|
S |
3.4.14.4 |
PF3D7_1471100 |
|
|
exported protein 2 |
S |
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0404700 |
|
|
dipeptidyl aminopeptidase 3 |
|
|
|
S |
3.4.14.4 |
PF3D7_0207600 |
|
|
serine repeat antigen 5 |
|
S |
S |
S |
3.4.22.- |
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0405900 |
|
|
apical sushi protein |
|
|
|
S |
|
PF3D7_1473200 |
|
|
DnaJ protein, putative |
|
S |
S |
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0500800 |
|
|
erythrocyte membrane protein 2 mature parasite-infected erythrocyte surface antigen |
|
S |
S |
S |
|
PF3D7_0903600 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0501300 |
|
|
skeleton-binding protein 1 |
S |
S |
S |
S |
|
PF3D7_1335400 |
|
|
reticulocyte binding protein 2 homologue a |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0532400 |
|
|
lysine-rich membrane-associated PHISTb protein |
|
S |
S |
S |
|
PF3D7_0703200 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0904600 |
|
|
ubiquitin specific protease, putative |
|
S |
S |
S |
3.4.19.12 |
PF3D7_1335100 |
|
|
merozoite surface protein 7 |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0918200 |
|
|
50S ribosomal protein L3, apicoplast, putative |
S |
S |
S |
S |
|
PF3D7_1210000 |
|
|
50S ribosomal protein L1, apicoplast, putative |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PF3D7_0930300 |
|
|
merozoite surface protein 1 |
S |
S |
S |
S |
|
PF3D7_1335800 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|