Protein kinase G-dependent phosphorylation in schizonts
Alam MM, Solyakov L, Bottrill AR, Flueck C, Siddiqui FA, Singh S, Mistry S, Viskaduraki M, Lee K, Hopp CS, Chitnis CE, Doerig C, Moon RW, Green JL, Holder, AA, Baker DA, Tobin AB. Phosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion. Nat Commun. 2015 Jul 7;6:7285.
PfID Annotation P-site EC Transcript
Invasion/egress-related proteins
14066 PF3D7_0414900
armadillo-domain containing rhoptry protein s2346
14097 PF3D7_1149000
antigen 332, DBL-like protein s33, s36
14100 PF3D7_1251200
coronin s570, s571
14078 PF3D7_0623100 nuclear polyadenylated rna-binding protein nab2 s120
14107 PF3D7_1434500 dynein-related AAA-type ATPase, putative s7014 3.6.4.2
14070 PF3D7_0515700
glideosome-associated protein 40, putative t433, s436, s445, s446
14099 PF3D7_1222700
glideosome-associated protein 45 s149, s156
14065 PF3D7_0316700 protein yop1, putative s28
14072 PF3D7_0525800
inner membrane complex protein 1g, putative s274, s277
14104 PF3D7_1342600
myosin A s19
14075 PF3D7_0613900 myosin E, putative s1084, s1088
14091 PF3D7_1021800
schizont egress antigen-1 s280
Transporters
14062 PF3D7_0106300
calcium-transporting ATPase, ATP6 s482 3.6.3.8
14068 PF3D7_0504000 cation transporting P-ATPase, ATPase3 s1028 3.6.3.12
14101 PF3D7_1304200 CorA-like Mg2+ transporter protein, putative, MIT2 s72, s75
14105 PF3D7_1347200
nucleoside transporter 1, NT1 s8, s16
14086 PF3D7_0824400
nucleoside transporter 2, NT2 s324, s353, s372
27702 PF3D7_0614300 major facilitator superfamily-related transporter, MFR1 s435, s530
14103 PF3D7_1340900
sodium-dependent phosphate transporter, PiT s361
27687 PF3D7_0312500
apicomplexan amino acid transporter apiat10 s577
14094 PF3D7_1129900
apicomplexan amino acid transporter apiat4 s34
Proteolysis
14069 PF3D7_0506900
rhomboid protease ROM4 s92, s94/ s158, s160 3.4.21.105
23991 PF3D7_0907700 proteasome activator 28 s92
14088 PF3D7_0922100
ubiquitin-like protein, putative s931
Signalling proteins
14102 PF3D7_1321500
3',5'-cyclic nucleotide phosphodiesterase beta s156 3.1.4.17
14085 PF3D7_0802600
Adenylyl cyclase, Acb s1572 4.6.1.1
14063 PF3D7_0217500
Calcium-dependent protein kinases; CDPK1 s64 2.7.11.1
14095 PF3D7_1138400
guanylyl cyclase alfa Gca s674, s4203 4.6.1.2
23849 PF3D7_0709700
monoglyceride lipase s14 3.1.-.-
14071 PF3D7_0516400 phosducin-like protein 1, putative s306, s309, s310
Transcriptional regulation
15694 PF3D7_1006800
G-strand-binding protein 2 s92
25579 PF3D7_1002400 transformer-2 protein homolog beta, putative s238
23684 PF3D7_0730300
AP2 domain transcription factor AP2-L, putative s948
14096 PF3D7_1142500 60S ribosomal protein L28 s98
25797 PF3D7_1360900 RNA-binding protein, putative s195
Export proteins
14067 PF3D7_0424600
plasmodium exported protein (phistb) t124
14084 PF3D7_0730900
EMP1-trafficking protein s1178/s1274/s1370/s1466/s1562/s1458
Chromatin regulation
14093 PF3D7_1105100
histone H2B t14
14073 PF3D7_0610400
histone H3 s29, s33
23808 PF3D7_0617900
histone H3 variant s29, s33, t34
14082 PF3D7_0711500 regulator of chromosome condensation, putative s600, s603, s676
14080 PF3D7_0624600
iswi chromatin-remodeling complex atpase s1898 3.6.4.12
14098 PF3D7_1212900
bromodomain protein 2, putative s408
15949 PF3D7_0611400
swi/snf-related matrix-associated actin-dependent regulator of chromatin s104
Other
14092 PF3D7_1027300
peroxiredoxin merozoite capping protein 1 s327, s329, t330 1.11.1.15
14079 PF3D7_0624000
hexokinase t18 2.7.1.1
+23 unchharacterized proteins,
6 of which are are proteins that share an association
with the motor complex, suggesting that they might function as motor-associated proteins
Online articles related to Protein kinase G-dependent phosphorylation in schizonts retrieved from PubMed