Localization of Pf38 fused to a GFP reporter and expressed in an inducible system that allows strong surface expression. MS, mid-schizont; LS, late schizont; M, merozoite. Pf38-GFP was mostly concentrated in secretory organelles at the apical end of the parasite, exclusively at an early stage of schizont development, suggesting that Pf38 probably predominantly resides in these apical organelles. Pf38 is a GPI-anchored protein.
Sanders PR, Gilson PR, Cantin GT, Greenbaum DC, Nebl T, Carucci DJ, McConville MJ, Schofield L, Hodder AN, Yates JR 3rd, Crabb BS. Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum. J Biol Chem. 2005 280:40169-76.