Mitochondrial localization of GFP-tagged PfMDM2 within live Plasmodium falciparum parasites, directed by the protein’s N-terminus. Live imaging of the PfMDM2-GFP transgenic P. falciparum parasites under normal conditions. A distinct dot-like GFP signal was observed for PfMDM2, adjacent to the blue DAPI-stained nucleus, increasing in number with the progression of the life cycle. The truncated PfMDM2 protein lacking the N-terminus showed cytoplasmic distribution of the GFP signal.

Vieira WA, Coetzer TL. Localization and interactions of Plasmodium falciparum SWIB/MDM2 homologues. Malar J. 2016 Jan 20;15(1):32.