Localization of PfDOC2. Confocal immunofluorescence microscopy using anti-PfDOC2 antisera. (A) PfDOC2 labeled cells were visualized with Alexa 488 (green); (B) Blue: DAPI stains the nucleus of infected cells. (C) PfDOC2 and DAPI overlay. (D) DIC: differential interference contrast. PfDOC2 is expressed throughout the erythrocytic cycle and demonstrate that it is associated with membrane fractions and binds to calcium when it is part of these membranous structures.

Jean S, Zapata-Jenks MA, Farley JM, Tracy E, Mayer DC. Plasmodium falciparum double C2 domain protein, PfDOC2, binds to calcium when associated with membranes. Exp Parasitol. 2014 144C:91-95. PMID: 24992295