You can find more information about
using the following links:
PlasmoDB - the Plasmodium genome resource
The TDR Targets Database
Affecting Drugs
Drug Name
PubMed Articles (year of publication)
Cycloguanil
dCTP levels are maintained in Plasmodium falciparum subjected to pyrimidine deficiency or excess(1997)
A bifunctional dihydrofolate synthetase--folylpolyglutamate synthetase in Plasmodium falciparum identified by functional complementation in yeast and bacteria(2001)
Phosphinate
Characterisation of the bifunctional dihydrofolate synthase-folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition(2010)
Proguanil
A bifunctional dihydrofolate synthetase--folylpolyglutamate synthetase in Plasmodium falciparum identified by functional complementation in yeast and bacteria(2001)
Pyrimethamine
A bifunctional dihydrofolate synthetase--folylpolyglutamate synthetase in Plasmodium falciparum identified by functional complementation in yeast and bacteria(2001)
Sulfadoxine
A bifunctional dihydrofolate synthetase--folylpolyglutamate synthetase in Plasmodium falciparum identified by functional complementation in yeast and bacteria(2001)
Wr99210
dCTP levels are maintained in Plasmodium falciparum subjected to pyrimidine deficiency or excess(1997)