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PFID PFID Old Formal Annotation PlasmoDB TDR Targets Subcellular Localization Affecting Drugs
Drug Name PubMed Articles (year of publication)
PF3D7_0102600 PFA0130c serine/threonine protein kinase, FIKK family PlasmoDB TDR
PF3D7_0107600 PFA0380w eukaryotic translation initiation factor 2-alpha kinase 2 PlasmoDB TDR
PF3D7_0203100 PFB0150c protein kinase, putative PlasmoDB TDR
In silico prediction of protein targets of antimalarial compounds, suggested target
PF3D7_0211700 PFB0520w tyrosine kinase-like protein, putative PlasmoDB TDR
Imatinib mesylate
Sorafenib Tosylate
PF3D7_0213400 PFB0605w protein kinase 7 PlasmoDB TDR
1nm-pp1
3-(1,2,3-triazol-4-yl)pyrazolo[3,4-d]pyrimidin
Hymenialdisine
Hymenialdisine 01
Imidazopyridazine
Luzindole
Melatonin
Pp2
pyrazolo[3,4-d]pyrimidin-4-amine
Staurosporine
TCMDC-136692
TCMDC-136693
PF3D7_0214600 PFB0665w serine/threonine protein kinase stk2, putative PlasmoDB TDR
PF3D7_0301200 PFC0060c serine/threonine protein kinase, FIKK family PlasmoDB TDR
PF3D7_0302100 PFC0105w serine/threonine protein kinase PlasmoDB TDR
4-(1h)-quinolone
Aminopyrimidines
Annomontin
In silico prediction of protein targets of antimalarial compounds, suggested target
PF3D7_0309200 PFC0385c serine/threonine protein kinase ark2, putative PlasmoDB TDR
In silico prediction of protein targets of antimalarial compounds, suggested target
PF3D7_0312400 PFC0525c glycogen synthase kinase 3 PlasmoDB TDR
3,6-diamino-4-(2-bromophenyl)-2-(3,4-dichlorobenzoyl)thieno[2,3-b]pyridine-5-carbonitrile
3,6-diamino-4-(2-bromophenyl)-2-(3-chlorobenzoyl)thieno[2,3-b]pyridine-5-carbonitrile
3,6-diamino-4-(2-halophenyl)-2-benzoylthieno[2,3-b]pyridine-5-carbonitriles
3,6-diamino-4-(thiophen-2-yl)thieno[2,3-b]pyridine-2,5-dicarbonitrile​
3,6-diamino-4-o-tolylthieno[2,3-b]pyridine-2,5-dicarbonitrile
4-((5-Chloro-4-(5-methylthiophen-2-yl)pyrimidin-2-yl)amino)-N- (3-morpholinopropyl)benzamide (23f)
4-[(6-methoxy-1-benzofuran-2-yl)carbonyl]benzonitrile
4-phenylthieno[2,3-b]pyridine
Actinomyces strain FH025
Actinomyces strain H11809
CHIR 99021
Curcumin
In silico, suggested target
indirubin-30-monoxime
Indirubins
Manzamine a
Meridians
Paullone
Quinazolinone
Structure-based design, suggested target
PF3D7_0420100 PFD0975w serine/threonine protein kinase RIO2 PlasmoDB TDR
(1r,2r,3s,5s)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1] octane-2-carboxylic acid
8-hydroxy-4-methyl-9-nitro-2h-benzo[g]chromen-2-one
Apigenin
E-64
Ecgonine
Enzastaurin
Ethyl loflazepate
In silico drug design suggested target
Indirubin-3'-monoxime
Kaempferol
Ketotifen
Leupeptin
Pepstatin
Pfrio2-atp-dna complex formation, suggested target
Pmsf
Wortmannin
PF3D7_0424500 PFD1165w serine/threonine protein kinase, FIKK family PlasmoDB TDR
PF3D7_0424700 PFD1175w serine/threonine protein kinase, FIKK family PlasmoDB TDR
PF3D7_0500900 PFE0045c serine/threonine protein kinase, FIKK family PlasmoDB TDR
PF3D7_0525900 PFE1290w NIMA related kinase 2 PlasmoDB TDR
4-[(6-ethynyl-9H-purin-2-yl)amino]benzenesulfonamide
PF3D7_0605300 PFF0260w erine/threonine protein kinase ark1 PlasmoDB TDR
AZD-1152-HQPA
Essential suggested target
Hesperadin
PF3D7_0704500 MAL7P1.18 serine/threonine protein kinase, putative PlasmoDB TDR
PF3D7_0718100 MAL7P1.91 exported serine/threonine protein kinase PlasmoDB TDR
PF3D7_0719200 MAL7P1.100 NIMA related kinase 4 PlasmoDB TDR
PF3D7_0724600 MAL7P1.132 protein kinase, putative PlasmoDB TDR
PF3D7_0726200 MAL7P1.144 serine/threonine protein kinase, FIKK family PlasmoDB TDR
PF3D7_0731400 MAL7P1.175 serine/threonine protein kinase, FIKK family, pseudogene PlasmoDB TDR
PF3D7_0805700 MAL8P1.203 serine/threonine protein kinase, FIKK family PlasmoDB TDR
emodin
PF3D7_0821100 PF08_0044 protein kinase 1 PlasmoDB TDR
PF3D7_0902000 PFI0095c serine/threonine protein kinase, FIKK family PlasmoDB TDR
PF3D7_0902100 PFI0100c serine/threonine protein kinase, FIKK family PlasmoDB TDR
PF3D7_0902200 PFI0105c serine/threonine protein kinase, FIKK family PlasmoDB TDR
PF3D7_0902300 PFI0110c serine/threonine protein kinase, FIKK family PlasmoDB TDR
PF3D7_0902400 PFI0115c serine/threonine protein kinase, FIKK family PlasmoDB TDR
PF3D7_0902500 PFI0120c serine/threonine protein kinase, FIKK family PlasmoDB TDR
PF3D7_0902600 PFI0125c serine/threonine protein kinase, FIKK family PlasmoDB TDR
PF3D7_0926300 PFI1285w protein kinase, putative PlasmoDB TDR
PF3D7_0928800 PFI1415w serine/threonine protein kinase, putative PlasmoDB TDR
PF3D7_1016400 PF10_0160 serine/threonine protein kinase, FIKK family PlasmoDB TDR
2-[3-[1-[3-[2-[[3-azido-5-(azidomethyl)phenyl]methoxy]ethyl]cyclopenta-1,3-dien-1-yl]ethyl]-4-methyl-thiazol-5-yl]ethanol
PF3D7_1039000 PF10_0380 serine/threonine protein kinase, FIKK family PlasmoDB TDR
PF3D7_1103700 PF11_0048 casein kinase II beta chain PlasmoDB TDR
Carbazole
Functional analysis, difference from host, suggested target
PF3D7_1108400 PF11_0096 casein kinase 2, alpha subunit PlasmoDB TDR
5-(3-chloroanilino)benzo[c][2,6]naphthyridine-8-carboxylic acid
Carbazole
Ml-7
Rottlerin
PF3D7_1114700 PF11_0156 cyclin-dependent-like kinase clk3 PlasmoDB TDR
4-(2-{2-Methoxy-5-[(morpholin-4-yl)methyl]phenyl}-1H-pyrrolo[2,3-b]pyridin-4-yl)-2-(propan-2-yl)benzoic Acid
Altiratinib
Aminopyrimidines
Oxo-b-carbolines
TCMDC-135051
PF3D7_1121900 PF11_0227 3-phosphoinositide-dependent protein kinase 1 PlasmoDB TDR
PF3D7_1136500 PF11_0377 casein kinase 1 PlasmoDB TDR
(2R)-2-[[6-(3-chloroanilino)-9-propan-2-ylpurin-2-yl]amino]-3-methylbutan-1-ol
aminopurvalanol
In silico prediction of protein targets of antimalarial compounds, suggested target
isopentenyladenine
methyl-aminopurvalanol
Methyl-purvalanol B
Olomoucine
Purvalanol b
Roscovitine
PF3D7_1145200 PF11_0464 serine/threonine protein kinase, putative PlasmoDB TDR
PF3D7_1148000 PF11_0488 serine/threonine protein kinase, putative PlasmoDB TDR
BI-2536
In silico prediction of protein targets of antimalarial compounds, suggested target
PF3D7_1149300 PF11_0510 serine/threonine protein kinase, FIKK family PlasmoDB TDR
PF3D7_1200800 PFL0040c serine/threonine protein kinase, FIKK family PlasmoDB TDR
PF3D7_1201600 PFL0080c NIMA related kinase 3 PlasmoDB TDR
PF3D7_1228300 PFL1370w NIMA related kinase 1 PlasmoDB TDR
(2R)-2-[[6-[(3-amino-5-chloro-phenyl)methyl]-9-isopropyl-purin-2-yl]amino]-3-methyl-butan-1-ol
Alisiaquinol
Alisiaquinone A
Alisiaquinone B
Alisiaquinone C
Drugs not specified, suggeted target
Hesperadin
Hymenialdisine 01
Methyl (2,4-dibromo- 3,6-dihydroxyphenyl) acetate
Purvalanol
Roscovitine
Xestoquinone
PF3D7_1230900 PFL1490w serine/threonine protein kinase RIO1, putative PlasmoDB TDR
In silico prediction of protein targets of antimalarial compounds, suggested target
PF3D7_1246900 PFL2250c RAC-beta serine/threonine protein kinase PlasmoDB TDR
Calmodulin, phospholipase c
Dihydroartemisinin
In silico prediction of protein targets of antimalarial compounds, suggested target
PF3D7_1247500 PFL2280w serine/threonine protein kinase, putative PlasmoDB TDR
In silico prediction of protein targets of antimalarial compounds, suggested target
PF3D7_1338900 MAL13P1.196 serine/threonine protein kinase, putative PlasmoDB TDR
PF3D7_1342400 PF13_0232 casein kinase II beta chain PlasmoDB TDR
Functional analysis, difference from host, suggested target
PF3D7_1356800 MAL13P1.278 serine/threonine protein kinase ark3, putative PlasmoDB TDR
Suggested target
PF3D7_1428500 PF14_0264 protein kinase, putative PlasmoDB TDR
PF3D7_1433900 PF14_0320 protein kinase, putative PlasmoDB TDR
PF3D7_1441300 PF14_0392 serine/threonine protein kinase, putative PlasmoDB TDR
PF3D7_1443000 PF14_0408 serine/threonine protein kinase PlasmoDB TDR
Aminopyrimidines
Annomontin
Oxo-b-carbolines
PF3D7_1445400 PF14_0431 protein serine/threonine kinase-1 PlasmoDB TDR
(2R)-2-[[3-[3-[(E)-[(1R)-1-(hydroxymethyl)propyl]iminomethyl]phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]butan-1-ol
Aminopyrimidines
Annomontin
Oxo-b-carbolines
PF3D7_1476400 PF14_0733 serine/threonine protein kinase, FIKK family, pseudogene PlasmoDB TDR
Expasy - NiceZime View
Brenda - The Comprehensive Enzyme Information System