You can find more information about
Dihydroorotase
using the following links:
PFID
PFID Old
Formal Annotation
PlasmoDB
TDR Targets
Subcellular Localization
Affecting Drugs
Drug Name
PubMed Articles (year of publication)
PF3D7_1472900
PF14_0697
dihydroorotase, putative
PlasmoDB
TDR
5-amino orotate
Antimalarial activity of orotate analogs that inhibit dihydroorotase and dihydroorotate dehydrogenase
5-bromo orotate
Antimalarial activity of orotate analogs that inhibit dihydroorotase and dihydroorotate dehydrogenase
5-fluoroorotate
Antimalarial activity of orotate analogs that inhibit dihydroorotase and dihydroorotate dehydrogenase
5-methyl orotate
Antimalarial activity of orotate analogs that inhibit dihydroorotase and dihydroorotate dehydrogenase
dynasore
Antimalarial activity of orotate analogs that inhibit dihydroorotase and dihydroorotate dehydrogenase
genz-669178
Harnessing evolutionary fitness in Plasmodium falciparum for drug discovery and suppressing resistance
Suggested target
Cloning and expression of malarial pyrimidine enzymes
Tdho
dCTP levels are maintained in Plasmodium falciparum subjected to pyrimidine deficiency or excess
Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis
Expasy - NiceZime View
Brenda - The Comprehensive Enzyme Information System
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