You can find more information about ATP-dependent DNA helicase UvrD using the following links:

PFID

PFID Old

Formal Annotation

PlasmoDB

TDR Targets

Subcellular Localization

Affecting Drugs

Drug Name

PubMed Articles (year of publication)

PF3D7_0514100

PFE0705c

ATP-dependent DNA helicase UvrD

Picture 1

Daunorubicin	Plasmodium falciparum UvrD activities are downregulated by DNA-interacting compounds and its dsRNA inhibits malaria parasite growth
Difference from host orthologue, suggested target	UvrD helicase of Plasmodium falciparum
Ethidium bromide	Plasmodium falciparum UvrD activities are downregulated by DNA-interacting compounds and its dsRNA inhibits malaria parasite growth
Interaction with dna mismatch repair protein mlh (pf11_0184), suggested target	Plasmodium falciparum UvrD helicase translocates in 3' to 5' direction, colocalizes with MLH and modulates its activity through physical interaction
Netropsin	Plasmodium falciparum UvrD activities are downregulated by DNA-interacting compounds and its dsRNA inhibits malaria parasite growth
Nogalamycin	Plasmodium falciparum UvrD activities are downregulated by DNA-interacting compounds and its dsRNA inhibits malaria parasite growth
Suggested target	In silico analysis of Plasmodium species specific UvrD helicase

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Brenda - The Comprehensive Enzyme Information System