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Subcellular Localization

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Affecting Drugs
Drug Name	PubMed Articles (year of publication)
(3,4-dihydroquinolin-1(2H)-yl)(1-(1-phenyl-1H-tetrazol-5-yl)piperidin-4-yl)methanone	Exploring a Tetrahydroquinoline Antimalarial Hit from the Medicines for Malaria Pathogen Box and the Identification of its Mode of Resistance as PfeEF2(2022)
1-[6-fluoro-2-[4-(morpholinomethyl)phenyl]-4-quinolyl]-2-(pyrrolidin-1-ylmethylamino)ethanone	A novel multiple-stage antimalarial agent that inhibits protein synthesis(2015)
6-Fluoro-2-[4-(4-morpholinylmethyl)phenyl]-N-[2-(1-pyrrolidinyl)ethyl]-4-quinolinecarboxamide	Using in Vitro Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery(2018)
6-fluoro-2-[4-(morpholin-4-ylmethyl)phenyl]-N-(2-pyrrolidin-1-ylethyl)quinoline-4-carboxamide	Preclinical Antimalarial Combination Study of M5717, a Plasmodium falciparum Elongation Factor 2 Inhibitor, and Pyronaridine, a Hemozoin Formation Inhibitor(2020)
DDD498	Metabolomic Profiling of the Malaria Box Reveals Antimalarial Target Pathways(2016)
Doxycycline	Plasmodium falciparum proteome changes in response to doxycycline treatment(2010)