You can find more information about glyceraldehyde-3-phosphate dehydrogenase using the following links:

Subcellular Localization

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PDB protein strucure

• 1YWG
• 2B4R
• 2B4T

Affecting Drugs
Drug Name	PubMed Articles (year of publication)
(S)-Methyl 2-Amino-2-((S)-3-bromo-4,5-dihydroisoxazol-5-yl)acetate	Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria(2014)
2-anilinotetralin-1,4-dione	Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule(2017)
2-phenoxytetralin-1,4-dione	Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule(2017)
3-bromo-5-(4-methoxyphenyl)-4,5-dihydroisoxazole	Selectivity of 3-bromo-isoxazoline inhibitors between human and Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenases(2016)
3-Bromo-5-phenyl-4,5-dihydroisoxazole	Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria(2014)
Asteriscunolide A	Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry(2018)
Chloroquine	Chloroquine mediates specific proteome oxidative damage across the erythrocytic cycle of resistant Plasmodium falciparum(2008)
Ferriprotoporphyrin ix	Identification and characterization of heme-interacting proteins in the malaria parasite, Plasmodium falciparum(2003)
fosmidomycin	GAPDH mediates drug resistance and metabolism in Plasmodium falciparum malaria parasites(2022)
H2O2	Loss of pH control in Plasmodium falciparum parasites subjected to oxidative stress(2013)
methyl (2S)-2-amino-2-[(5S)-3-bromo-4,5-dihydroisoxazol-5-yl]acetate	Selectivity of 3-bromo-isoxazoline inhibitors between human and Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenases(2016)
methyl (S)-2-amino-2-((S)-3-bromo-4,5-dihydroisoxazol-5-yl)acetate	Covalent Inhibitors of Plasmodium falciparum Glyceraldehyde 3-Phosphate Dehydrogenase with Antimalarial Activity in Vitro(2019)
Molecular charcterization, suggested target	Cloning, expression, purification and characterization of Plasmodium spp. glyceraldehyde-3-phosphate dehydrogenase(2016)
Suggested target	Structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum(2005) Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site(2006)