You can find more information about PF3D7_1457000-Signal peptidase using the following links:

Subcellular Localization

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Affecting Drugs
Drug Name	PubMed Articles (year of publication)
(Z-LL)2 ketone	Differential Inhibition of Signal Peptide Peptidase Family Members by Established ?-Secretase Inhibitors(2015)
(z-ll)2-ketone and	Plasmodium falciparum signal peptide peptidase is a promising drug target against blood stage malaria(2009)
173550-33-9	Differential Inhibition of Signal Peptide Peptidase Family Members by Established ?-Secretase Inhibitors(2015)
208255-80-5	Differential Inhibition of Signal Peptide Peptidase Family Members by Established ?-Secretase Inhibitors(2015)
209986-17-4	Differential Inhibition of Signal Peptide Peptidase Family Members by Established ?-Secretase Inhibitors(2015)
292632-98-5	Differential Inhibition of Signal Peptide Peptidase Family Members by Established ?-Secretase Inhibitors(2015)
Chembl302004	Plasmodium falciparum signal peptide peptidase is a promising drug target against blood stage malaria(2009)
LY-411,575	Differential Inhibition of Signal Peptide Peptidase Family Members by Established ?-Secretase Inhibitors(2015)
Ly-411575	Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic design(2012)
Nitd679	Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic design(2012)
Nitd731	Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic design(2012) Using genetic methods to define the targets of compounds with antimalarial activity(2013)
Ron5 derived peptides	Using genetic methods to define the targets of compounds with antimalarial activity(2013)
Thapsigargin	Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic design(2012)
Thiaisoleucine	Using genetic methods to define the targets of compounds with antimalarial activity(2013)
YO-01027	Characterization of SPP inhibitors suppressing propagation of HCV and protozoa(2017)