Conditional disruption of ACβ expression. IFA showing localisation of ACβ-HA3 in close proximity to the rhoptry protein ARO (PF3D7_0414900) in schizonts, and ablation of expression by RAP treatment. Over 99% of all RAP-treated ACβ-HA:loxP schizonts examined by IFA were HA-negative in three independent experiments. Scale bar, 10 μm. ACβ, adenylyl cyclase beta; ARO, armadillo repeats only protein;
Patel A, Perrin AJ, Flynn HR, Bisson C, Withers-Martinez C, Treeck M, Flueck C, Nicastro G, Martin SR, Ramos A, Gilberger TW, Snijders AP, Blackman MJ, Baker DA. Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery. PLoS Biol. 2019 May 10;17(5):e3000264. PMID: 31075098
PubMed Article: Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0414900 | armadillo-domain containing rhoptry protein |