IFA analysis of ARP6-HA::ARP4-Ty1Cas9i. Nuclei were stained with Hoechst 33342 (blue fluorescence). The green fluorescence represents ARP4-Ty1 and the red fluorescence represents ARP6-HA. IFA reveals the co-localization of ARP4 and ARP6 in the nucleus. Bar = 5 mm. ARP6 and ARP4 in parasite cells. showed the two proteins co-localized in the, which indicated that ARP4 and ARP6 in P. falciparum have similar functions to those in yeast.

Zhao Y, Wang F, Wang C, Zhang X, Jiang C, Ding F, Shen L, Zhang Q. Optimization of CRISPR/Cas System for Improving Genome Editing Efficiency in Plasmodium falciparum. Front Microbiol. 2021 11:625862.