PfKMT1 and genes enriched in H3K9me3 are positioned at the nuclear periphery. Immuno-fluorescence assays using antibodies against H3K9me3 H3 (right) and the P. falciparum putative H3K9 methyltransferase PfKMT1 (left). 3D7 parasites are in late schizont (main image) and ring stage (top-right square). Nuclear DNA was detected with DAPI (red).
Lopez-Rubio JJ, Mancio-Silva L, Scherf A. Genome-wide analysis of heterochromatin associates clonally variant gene regulation with perinuclear repressive centers in malaria parasites. Cell Host Microbe. 2009 5:179-90.
PubMed Article: Genome-wide analysis of heterochromatin associates clonally variant gene regulation with perinuclear repressive centers in malaria parasites
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0610400 | histone H3 |
PF3D7_0617900 | histone H3 variant |
PF3D7_1333700 | histone H3-like centromeric protein CSE4 |