PfERC is not required for protein trafficking or organellar biogenesis. Representative TEM images of synchronized PfERC-glmS and PfERC-M9 schizonts grown for 48 h with GlcN and incubated with C1 for 4 h (n=2 biological replicates). Small arrowheads (white) point to micronemes, while large arrowheads (black) point to rhoptries. Bar, 200 nm. PfERC-glmS (PfERC tagged with the inducible version of the ribozyme gene, glmSn; 2 biological replicates) and PfERC-M9 (inactive version of the ribozyme, M9),

Fierro MA, Asady B, Brooks CF, Cobb DW, Villegas A, Moreno SNJ, Muralidharan V. An Endoplasmic Reticulum CREC Family Protein Regulates the Egress Proteolytic Cascade in Malaria Parasites. mBio. 2020 Feb 25;11(1). pii: e03078-19.