Indirect immunofluorescence images of P. falciparum schizonts stained with rabbit IgG (green) induced by 10 viral-vectored vaccines expressing malaria antigens, and negative control vectors lacking a malaria antigen. Nuclei are counterstained with 4,6-diamidino-2-phenylindole (blue). All sera were tested against 3D7 strain parasites, with the exception of anti-PfRH1 for which FVO strain parasites were used. All images to same scale as Giemsa stained image (top left, on which scale bar indicates 5 μm).
Douglas AD, Williams AR, Illingworth JJ, Kamuyu G, Biswas S, Goodman AL, Wyllie DH, Crosnier C, Miura K, Wright GJ, Long CA, Osier FH, Marsh K, Turner AV, Hill AV, Draper SJ. The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody. Nat Commun. 2011 2:601.
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0402300 | reticulocyte binding protein homologue 1 normocyte binding protein 1 |
PF3D7_0424100 | reticulocyte binding protein homologue 5 |
PF3D7_0424200 | reticulocyte binding protein homologue 4 |
PF3D7_0501500 | rhoptry-associated protein 3 |
PF3D7_0508000 | 6-cysteine protein |
PF3D7_0731500 | erythrocyte binding antigen-175 |
PF3D7_0930300 | merozoite surface protein 1 |
PF3D7_1228600 | merozoite surface protein 9 |
PF3D7_1335400 | reticulocyte binding protein 2 homologue a |