PF3D7_1353600 ER lumen protein retaining receptor

Stage-specific localization of apicoplast-targeted GFP and the effects of brefeldin A (bfa). Distribution of green fluorescence and PfBiP (red) in a early-ring (A, i–iii) and a trophozoite (B, i–iii; a late, 33 h, trophozoite with two nuclei stained in blue is shown). Distribution of green fluorescence and indicated secretory marker (red) in: rings incubated with Bfa for 24 h (C, i–iii); rings incubated with Bfa for 24 h, washed, and grown for 18 h in absence of drug (D, i–iii; E, i–iii); and trophozoites incubated with or without Bfa (F, i–iii). Blue indicates DNA stained with Hoechst 33342. White arrows in B, ii, D, ii, and E, ii, indicate apicoplast DNA. Scale bars as indicated in microns.

Cheresh P, Harrison T, Fujioka H, Haldar K. Targeting the malarial plastid via the parasitophorous vacuole. J Biol Chem. 2002 277:16265-77.

Other associated proteins

PFID Formal Annotation
PF3D7_0917900 PfHsp70-2
img