In Plasmodium falciparum the HA-tagged GAPMs (Glideosome Associated Protein with Multiple membrane spans) co-localise with the inner membrane complex protein GAP45 but not the plasma membrane protein MSP119. Immunofluorescence images of PfGAPM1-HA (A & B) and PfGAPM3-HA (C & D) expressing P. falciparum schizonts probed with an anti-HA antibody and antibodies to either the IMC-resident protein PfGAP45 (A & C) or the MSP119 subunit of the plasma membrane protein MSP1 PFI1475w (B & D). PfGAPM1-HA and PfGAPM3-HA co-localize with PfGAP45 PFL1090w throughout development but not with MSP119 particularly during early schizogony.

Bullen HE, Tonkin CJ, O'Donnell RA, Tham WH, Papenfuss AT, Gould S, Cowman AF, Crabb BS, Gilson PR. A novel family of apicomplexan glideosome associated proteins with an inner-membrane anchoring role. J Biol Chem. 2009 284:25353-63.