The malaria infection-immunity-clock represents the 24-hour oscillations in host proteins and immune factors that play an essential role in host-pathogen interaction. Here we show circadian regulations of the components of four major host response pathways in malaria (FDR < 0.05, fold enrichment > 2.5, Count > 5). The clock symbols indicate the transcript level rhythmicity (JTK Q < 0.1, period 24 ± 3 hours) of that entity involved in that particular physiological pathway.

Rankawat S, Kundal K, Chakraborty S, Kumar R, Ray S. A comprehensive rhythmicity analysis of host proteins and immune factors involved in malaria pathogenesis to decipher the importance of host circadian clock in malaria. Front Immunol. 2023 14:1210299