Model for Stress Granule Assembly and Dynamicity Dashed lines between mRNPs represent weak physical interactions in the Phase-Separated Shell. Red wavy lines represent strong interactions between Prion-Like Domains. Possible sites of activity of the CCT, RVB and MCM complexes are also shown. Jain S, Wheeler JR, Walters RW, Agrawal A, Barsic A, Parker R. ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell. 2016 164(3):487-98. PMID: 26777405