between mRNPs represent weak physical interactions in the Phase-Separated Shell. Red wavy lines represent strong interactions between Prion-Like Domains. Possible sites of activity of the CCT, RVB and MCM complexes are also shown. Protter DSW, Parker R. Principles and Properties of Stress Granules. Trends Cell Biol. 2016 26(9):668-679. PMID: 27289443