The effect of Ala replacements within the SURFIN4.1-NTC N-terminal region for export in the P. falciparum line MS822. Live cell imaging of MS822-background transfectants expressing modified N4TC protein. N4TC serves as a background parasite. N4TC=N4 region fused to the transmembrane domain and a short cytoplasmic region.
Chitama BA, Miyazaki S, Zhu X, Kagaya W, Yahata K, Kaneko O. Multiple charged amino acids of Plasmodium falciparum SURFIN(4.1) N-terminal region are important for efficient export to the red blood cell. Parasitol Int. 2019. pii: S1383-5769(19)30092-3.