Anti-PfATRP rabbit antibody reacts with P. falciparum matured schizonts. (B) Dual IFA staining performed under permeabilized conditions using segmenting schizonts showed that a-PfAMA1 mouse antibody (red); (1:100) and a-PfATRP rabbit antibody (green); 1:100 labeled schizonts. . a-PfAMA1 mouse and a-PfATRP rabbit antibodies labeled the periphery of schizonts with dotty staining patterns suggesting an overlap of PfATRP with PfAMA1 (C) a-PfATRP rabbit antibody (red); (1:100) and a-PfMSP1 mouse antibody (green); (1:100) labeled schizonts. PfATRP is not likely localized on the merozoite surface. The nuclei were stained with DAPI. Black lines on IFA images represent scale bar. R signifies the colocalization coefficient
Amlabu E, Ilani P, Opoku G, Nyarko PB, Quansah E, Thiam LG, Anim M, Ayivor-Djanie R, Akuh OA, Mensah-Brown H, Rayner JC, Awandare GA. Molecular Characterization and Immuno-Reactivity Patterns of a Novel Plasmodium falciparum Armadillo-Type Repeat Protein, PfATRP. Front Cell Infect Microbiol. 2020 10:114. eCollection 2020.
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0930300 | merozoite surface protein 1 |
PF3D7_1133400 | apical membrane antigen 1 |