Expression and localisation of PfDHHC proteins in P. falciparum schizonts. Triple-HA-tagged PfDHHC proteins were localised by immunofluorescence using antibodies against the 3-HA tag (green). Immunofluorescence staining of each of the tagged PfDHHC proteins was compared against that of the following known localisation markers (red): ERD2 (Golgi marker), BIP (endoplasmic reticulum marker), RAP1 (rhoptry marker), GAP45 (inner membrane complex marker) and MSP1 (plasma membrane marker). Nuclear staining by DAPI is shown in blue. For the staining of PfDHHC9 with GAP45 and MSP1, both a late schizont, as well as an early schizont, is shown in order to differentiate between IMC and plasma membrane localisation. Scale bar: 5 μm.
Tay CL, Jones ML, Hodson N, Theron M, Choudhary JS, Rayner JC. Study of Plasmodium falciparum DHHC palmitoyl-transferases identifies a role for PfDHHC9 in gametocytogenesis. Cell Microbiol. 2016 Apr 6.
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0501600 | rhoptry-associated protein 2 |
PF3D7_0917900 | PfHsp70-2 |
PF3D7_0930300 | merozoite surface protein 1 |
PF3D7_1115900 | palmitoyltransferase DHHC9 |
PF3D7_1121000 | palmitoyltransferase DHHC3 |
PF3D7_1222700 | glideosome-associated protein 45 |
PF3D7_1322500 | palmitoyltransferase DHHC5 |
PF3D7_1353600 | ER lumen protein retaining receptor |