FRM1 and 2 show different cellular locations in asexual stage parasites. a Immunofluorescence microscopy of FRM1-HA parasites labelled with anti-HA (green) and anti-GAP45 (red). b anti-HA (green) and RON4 (red). DAPI (blue), merge and Differential interference contrast (DIC) images are shown. Scale bar = 5 μm. Dotted white line outlines the zoom panel. Zoom scale bar = 1 μm. c Live-cell immunofluorescence of FRM2-GFP (green) co-labelled with BODIPY-TR-Ceramide (Bodipy, red). DAPI (blue), merge and DIC images are shown. The dotted white line outlines the zoom panel. Zoom Scale bar = 1 μm.
Collier S, Pietsch E, Dans M, Ling D, Tavella TA, Lopaticki S, Marapana DS,
Shibu MA, Andrew D, Tiash S, McMillan PJ, Gilson P, Tilley L, Dixon MWA.
Plasmodium falciparum formins are essential for invasion and sexual stage
development. Commun Biol. 2023 6(1):861.
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_1116000 | rhoptry neck protein 4 |
PF3D7_1219000 | formin 2 |
PF3D7_1222700 | glideosome-associated protein 45 |