PfARK1 and PfARK2 localize to the intranuclear body in male late-stage gametocytes. (A, B) Localization of PfARK1–GFP and centrin (A) or PfARK2–GFP and centrin (B) in female and male stage IV gametocytes as assessed by IFAs. MTs were stained with antibodies against α/β-tubulin. Representative images are shown in each panel. DNA was stained with DAPI. DIC, differential interference contrast. A1/2, PfARK1/PfARK2; CEN, centrin; i, zoom selections. Scale bar = 5 µm. Wyss M, Thommen BT, Kofler J, Carrington E, Brancucci NMB, Voss TS. The three Plasmodium falciparum Aurora-related kinases display distinct temporal and spatial associations with mitotic structures in asexual blood stage parasites and gametocytes. mSphere. 2024 e0046524. PMID: 39235260.
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Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0309200 | serine/threonine protein kinase ark2, putative |
PF3D7_0702900 | centrin, putative |