Pfμ1 co-localizes with rhoptry marker proteins in schizont stage parasites. Transgenic parasites expressing Pfμ1–GFP were immunostained with antibodies specific to the Merozoite surface localized MSP1 (A), Microneme localized EBA175 (B), and Rhoptry localized RAP1 (C) and Clag3.1 (D). The parasite nuclei were stained with DAPI and slides were visualized by confocal microscopy. Representative images are shown for each antibody, together with DIC images; scale bars denote 5 μM. To quantify co-localisation, Pearson correlation coefficients of the individual stains were calculated and are shown in the right panel of each image. Kaderi Kibria KM, Rawat K, Klinger CM, Datta G, Panchal M, Singh S, Iyer GR, Kaur I, Sharma V, Dacks JB, Mohmmed A, Malhotra P. A role for adaptor protein complex 1 in protein targeting to rhoptry organelles in Plasmodium falciparum. Biochim Biophys Acta. 2015 1853(3):699-710. PMID: 25573429
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0302500 | cytoadherence linked asexual protein 3.1 |
PF3D7_0731500 | erythrocyte binding antigen-175 |
PF3D7_1311400 | AP-1 complex subunit mu-1 |
PF3D7_1410400 | rhoptry-associated protein 1 |