PF3D7_0729200 1-cys peroxiredoxin

Dual localization of PfAOP. (A) Immunofluorescence localization of PfAOP in blood stage parasites. (C) Co-localization analysis of PfAOP and a chimera of acyl-carrier protein and GFP (ACP-GFP) as an apicoplast-localized marker protein. Left, upper panel: a rather strong fluorescence was detected in the parasite cytosol.

Left: Cytosolic or apicoplast localization of mutated and truncated GFP-tagged PfAOP. Additional confocal live cell images of blood stage parasites expressing the indicated PfAOP-GFP chimera. Early trophozoite to late schizont stage parasites are shown from top to bottom for each construct. Scale bar, 5 μm. Unprocessed full length PfAOP was not observed.

Djuika CF, Huerta-Cepas J, Przyborski JM, Deil S, Sanchez CP, Doerks T, Bork P, Lanzer M, Deponte M. Prokaryotic ancestry and gene fusion of a dual localized peroxiredoxin in malaria parasites. Microb Cell. 2015 2(1):5-13.

Other associated proteins

PFID Formal Annotation
PF3D7_0208500 acyl carrier protein
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