Left: Localisation of AP-2μ-3xHA and Rab5B by immunoelectron microscopy Electron micrographs of vesicular colocalisation of AP-2μ-3xHA (18 nm gold particles) and Rab5B (12 nm gold particles) in developing trophozoites. N: nucleus; ER: endoplasmic reticulum; H: haemozoin; white arrowhead: AP-2μ at the nuclear membrane; black arrowhead: vesicles co-labelled for both proteins. Scale bar: 500 nm. Right: Localisation of AP-2μ-2xFKBPP-GFP and PDI by immunoelectron microscopy. Electron micrographs of vesicular colocalisation of AP-2μ-2xFKBP-GFP (18 nm gold particles) and PDI (12 nm gold particles) in developing trophozoites. N: nucleus; ER: endoplasmic reticulum; H: haemozoin; white arrowhead: AP-2μ at the nuclear membrane; black arrow: AP-2μ in vesicles; black arrowhead: AP-2μ at the ER. Scale bar: 500 nm.
Modification of an atypical clathrin-independent AP-2 adaptin complex of Plasmodium falciparum reduces susceptibility to artemisinin. Ryan C. Henrici, Rachel L. Edwards, Martin Zoltner, Donelly A. van Schalkwyk, Melissa N. Hart, Franziska Mohring, Robert W. Moon, Stephanie D. Nofal, Avnish Patel, Christian Flueck, David A. Baker, doi: https://doi.org/10.1101/621078
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_1218300 | AP-2 complex subunit mu |
PF3D7_1310600 | ras-related protein Rab-5B secretory complex protein 61 alpha |