PF3D7_0910600 SNARE protein

Model of RASP2 rhoptry docking/priming function in apicomplexan parasites. Upon response to an unknown signal, RASP2 binds to phospholipids (PA/PIP2) (a). This promotes association of the rhoptry with the parasite plasma membrane to initiate the assembly of the docking/primModel of RASP2 rhoptry docking/priming function in apicomplexan parasites. Upon response to an unknown signal, RASP2 binds to phospholipids (PA/PIP2) (a). This promotes association of the rhoptry with the parasite plasma membrane to initiate the assembly of the docking/priming machinery of the rhoptry (b), which results in membrane fusion, an essential step before the release of the rhoptry contents into the host cell (c). Suarez C, Lentini G, Ramaswamy R, Maynadier M, Aquilini E, Berry-Sterkers L, Cipriano M, Chen AL, Bradley P, Striepen B, Boulanger MJ, Lebrun M. A lipid-binding protein mediates rhoptry discharge and invasion in Plasmodium falciparum and Toxoplasma gondii parasites. Nat Commun. 2019 10(1):4041. PMID: 31492901;

Other associated proteins

PFID Formal Annotation
PF3D7_0314100 vesicle transport v-SNARE protein, putative
PF3D7_0530100 SNARE protein, putative
PF3D7_0826600 SNARE protein, putative
PF3D7_1236000 vesicle transport v-SNARE protein VTI1, putative
PF3D7_1303200 SNARE protein, putative
PF3D7_1320500 SNARE protein, putative
PF3D7_1324700 SNARE protein, putative
PF3D7_1448600 SNARE protein, putative
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