Analysis of the GBP130 N-terminal region. (B) Live cell imaging of parasites expressing GBP1-47 fused to GFP reveals that this region contains no targeting information. (C) Mutations within, or deletion of the transition areas have no effect on protein entry to the secretory system. Labels refer to the schematic in (A). DIC, differential interference contrast; GFP, green fluorescent protein; Hoechst, nuclear staining. In merge and overlay: green, GFP; blue, Hoechst. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.) Meyer C, Barniol L, Hiss JA, Przyborski JM. The N-terminal extension of the P. falciparum GBP130 signal peptide is irrelevant for signal sequence function. Int J Med Microbiol. 2018 308(1):3-12. PMID: 28750796.