Co-localization of PfEMP1 with Pf332, PfSbp1 and PfExp-1 in P. falciparum-infected erythrocytes. Double immuno-fluorescence images of infected erythrocytes at the trophozoite stage with antibodies against: (A) PfEMP1 (a-PfEMP1) and Pf332 (a-Pf332); B) PfEMP1 (a-PfEMP1) and PfSbp1 (a-PfSbp1); (C, D) PfEMP1 (a-PfEMP1) and PfExp-1 (a-PfExp1). Different morphological appearances of the structures stained with antibodies against PfEMP1 and PfExp-1 are shown in (C and D). (HOE), DNA staining by Hoechst. (overlay), Overlay of the micrographs shown in a row. Representative examples of three independent experiments are shown. Bar, 5 mm.
Wickert H, Wissing F, Andrews KT, Stich A, Krohne G, Lanzer M. Evidence for trafficking of PfEMP1 to the surface of P. falciparum-infected erythrocytes via a complex membrane network. Eur J Cell Biol. 2003 82:271-84.
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0501300 | skeleton-binding protein 1 |
PF3D7_1121600 | parasitophorous vacuole membrane antigen QF 116 exported protein 1 circumsporozoite-related antigen |
PfEMP1 | PfEMP1 |