PfmtRPS18 is likely localized to the mitochondrial inner membrane. A and B, images of D10-PfmtRPS18–3HA parasites. PVM, parasitophorous vacuole membrane; PPM, parasite plasma membrane; DV, digestive vacuole; ER, endoplasmic reticulum; M, mitochondrion. Black dots in red boxes indicate PfmtRPS18–3HA is localized to the mitochondrial inner membrane. C, a control with omission of the primary antibody shows a clear backgound. Data shown are representative of two biological experiments.

Ling L, Mulaka M, Munro J, Dass S, Mather MW, Riscoe MK, Llinás M, Zhou J, Ke H. Genetic ablation of the mitoribosome in the malaria parasite Plasmodium falciparum sensitizes it to antimalarials that target mitochondrial functions. J Biol Chem. 2020 295(21):7235-7248.