PF3D7_1251700 tryptophanyl-tRNA synthetase, putative tryptophan--tRNA ligase, putative

P. falciparum encodes cytosolic and apicoplast tryptophanyl-tRNA synthetase isoforms. The first panel shows live cell fluorescence microscopy of TrpRSapi-GFP and live mitochondrial staining, while the second and third panels show IFAs of P. falciparum TrpRSapi-GFP and TrpRScyt-GFP in relation to the apicoplast marker ACP. Schematic representations of transfected plasmids are indicated above each panel. ACP, acyl-carrier protein; DIC, differential interference contrast.

Pasaje CF, Cheung V, Kennedy K, Lim EE, Baell JB, Griffin MD, Ralph SA. Selective inhibition of apicoplast tryptophanyl-tRNA synthetase causes delayed death in Plasmodium falciparum. Sci Rep. 2016 6:27531.

Other associated proteins

PFID Formal Annotation
PF3D7_1336900 tryptophanyl-tRNA synthetase tryptophan--tRNA ligase
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