PF3D7_1301700 cx3cl1-binding protein 2, gametocyte exported protein 7, GEXP7

Genetic knockout of GEXP07 led to a loss of PfEMP1 at the RBC surface and impaired adhesion. (A) Wild-type CS2 and GEXP07 knockout-infected RBCs were fixed and probed with anti-PfEMP1 (green) and counter stained with anti-REX1 (red). Nuclei were stained with DAPI (blue). CS2 = parent line. Projections of Z stacks are shown. Scale bar = 5 μm. McHugh E, Carmo OMS, Blanch A, Looker O, Liu B, Tiash S, Andrew D, Batinovic S, Low AJY, Cho HJ, McMillan P, Tilley L, Dixon MWA. Role of Plasmodium falciparum Protein GEXP07 in Maurer's Cleft Morphology, Knob Architecture, and P. falciparum EMP1 Trafficking. mBio. 2020 11(2):e03320-19. PMID: 32184257

Other associated proteins

PFID Formal Annotation
PF3D7_0100300 erythrocyte membrane protein 1, PfEMP1
PF3D7_0115700 erythrocyte membrane protein 1, PfEMP1
PF3D7_0712000 erythrocyte membrane protein 1, PfEMP1
PF3D7_0935900 ring-exported protein 1
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