Localization of aminopeptidases in P. falciparum blood stages.
PfAPP Aminopeptidase P; PfA-M1 Aminopeptidase N; PfLAP Leucyl aminopeptidase; PfDAP Aspartyl aminopeptidase
B, Epifluorescence microscopy of live parasites expressing fusions of YFP with the indicated aminopeptidases. YFP fluorescence is pseudocolored green and Hoechst 33342 (DNA) fluorescence is pseudocolored red. The arrowhead indicates the food vacuole. Bar, 2 mm. C, indirect immunofluorescence detection of PfA-M1-HA. Secondary antibody fluorescence is pseudocolored green and DAPI (DNA) fluorescence is pseudocolored red. Bar, 2 mm.
Dalal S, Klemba M. Roles for two aminopeptidases in vacuolar hemoglobin catabolism in Plasmodium falciparum. J Biol Chem. 2007 282:35978-87.
PubMed Article: Roles for two aminopeptidases in vacuolar hemoglobin catabolism in Plasmodium falciparum
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0932300 | M18 aspartyl aminopeptidase |
PF3D7_1311800 | M1-family alanyl aminopeptidase |
PF3D7_1446200 | M17 leucyl aminopeptidase |