PhIL1 colocalize with ALV5, PhIP, and GAPM2 in the P. falciparum IMC. (A) ALV5-GFP expression pattern in asexual blood stages (merozoite, and schizont) of P. falciparum. (B) PhIP-GFP expression pattern in asexual blood stages showed typical IMC localization. (C) GAPM2-GFP expression pattern in asexual blood stages. (D) Co-staining of PhIL1 with ALV5, PhIP, and GAPM2 in P. falciparum blood-stage schizont. These proteins co-localized with PhIL1 in the IMC at the
schizont stage of the parasite with a Pearson’s colocalization coefficient of more than 0.7. Scale bar = 5 μm
Saini E, Sheokand PK, Sharma V, Agrawal P, Kaur I, Singh S, Mohmmed A, Malhotra P. Plasmodium falciparum PhIL1-associated complex plays an essential role in merozoite reorientation and invasion of host erythrocytes. PLoS Pathog. 2021 17(7):e1009750.
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_1003600 | inner membrane complex protein 1c, putative |
PF3D7_1310700 | PhIL1-interacting protein PhIP |