Subcellular localization of six putative P. falciparum transporters during
asexual blood stage development. (B–G) Localization of (B) PfFVRT1-GFP-glmS, (C) PfZIP1-GFP-glmS, (D) PfCDF-GFP-glmS, (E) PfDMT2-GFP-glmS, (F) PfMFS6-GFP-glmS and (G) PfPMRT1-GFP-glmS by live-cell microscopy in ring, trophozoite and schizont stage parasites. Nuclei were stained with Hoechst-33342. (H) Co654 localization of the GFP-tagged putative transporters with marker proteins P40PX-mCherry (food vacuole), ACP-mCherry (apicoplast), Lyn-mCherry (parasite plasma membrane), ARO656 mCherry (rhoptry) and AMA1-mCherry (microneme) as indicated. Nuclei were stained with Hoechst- 33342. Scale bar, 2 μm.
PubMed Article: PMRT1, a Plasmodium-Specific Parasite Plasma Membrane Transporter, Is Essential for Asexual and Sexual Blood Stage Development
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0609100 | zinc transporter zip1, putative |
PF3D7_0715900 | zinc transporter, putative |
PF3D7_0716900 | drug/metabolite transporter dmt2 |
PF3D7_1135300 | conserved Plasmodium membrane protein, unknown function |
PF3D7_1440800 | major facilitator superfamily domain-containing protein, MFS6 |