PF3D7_0934800 cAMP-dependent protein kinase catalytic subunit

STAD-2 does not associate with PKA. (A) Late-stage iRBC were treated with 1 μM FITC-conjugated STAD-2 for 2 hours and probed for P. falciparum PKA-R. STAD-2 did not show clear colocalization with the regulatory subunit.

Flaherty BR, Wang Y, Trope EC, Ho TG, Muralidharan V, Kennedy EJ, Peterson DS. The Stapled AKAP Disruptor Peptide STAD-2 Displays Antimalarial Activity through a PKA-Independent Mechanism. PLoS One. 2015 10(5):e0129239.

img