Dynamics of PfSec13-GFP during P. falciparum intra erythrocytic development. Conventional fluorescent imaging of PfSec13-GFP (Green) at different time points (hpi = hours post invasion) during the IDC. Strong signals of PfSec13-GFP at the periphery of the DAPI stained nucleus corresponds with NPC clusters. Dynamics in cluster number and orientation were documented from 1 hpi to 46 hpi. At the late schizont stage (from 38 hpi to 46 hpi) there is a change in NPC orientation. The size bar represents 1μm. The size bar represents 2 μm for 1, 16, 24, 38 & 48 hpi and 1 μm for 30 hpi. Strong signals are seen at the nuclear periphery and faint "background" in the cytoplasm.

Dahan-Pasternak N, Nasereddin A, Kolevzon N, Pe'er M, Wong W, Shinder V, Turnbull L, Whitchurch CB, Elbaum M, Gilberger TW, Yavin E, Baum J, Dzikowski R. PfSec13 is an unusual chromatin associated nucleoporin of Plasmodium falciparum, which is essential for parasite proliferation in human erythrocytes. J Cell Sci. 2013 126(Pt 14):3055-69 Reproduced with permission.