PfEMP1 PfEMP1

Immunofluorescence microscopy showing staggered delivery of different exomembrane components. (A-D) Infected RBCs were synchronized to a 1 h window, samples were collected at 2 h intervals and smears were fixed with acetone and stained with antibodies recognizing REX1, MAHRP1, SBP1, MAHRP2 and PfEMP1 (ATS) and co-stained with DAPI. Images are presented at time points before and after delivery to the RBC cytoplasm. Scale bars = 3 μm.

McMillan PJ, Millet C, Batinovic S, Maiorca M, Hanssen E, Kenny S, Muhle RA, Melcher M, Fidock DA, Smith JD, Dixon MW, Tilley L. Spatial and temporal mapping of the PfEMP1 export pathway in Plasmodium falciparum. Cell Microbiol. 2013 15(8):1401-18

Other associated proteins

PFID Formal Annotation
PF3D7_0501300 skeleton-binding protein 1
PF3D7_0935900 ring-exported protein 1
PF3D7_1353200 membrane associated histidine-rich protein 2
PF3D7_1370300 membrane associated histidine-rich protein
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