Confocal immunofluorescence microscopic images of P. falciparum schizonts treated with: Schizonts were stained with DAPI (nuclear stain), Alexafluor-488 (PfRAP1) and Alexafluor-546 (PfCYP19B). White scale bars indicate 5 μM. White arrows show characteristic bi-punctate rhoptry staining. Immuno-staining schizonts for RAP1 under normalconditions resulted in the bi-punctate staining characteristic of rhoptry proteins, while PfCYP19B waslocated in the cytoplasm as expected.

Leneghan D, Bell A. Immunophilin-protein interactions in Plasmodium falciparum. Parasitology. 2015 Jul 9:1-11. [Epub ahead of print] PubMed PMID: 26156578