Distribution of histones and their modifications throughout the intra-erythrocytic developmental cycle. a Immunofluorescence assay shows that PfH3K18ac, PfH3K27ac and PfH3K4me1 localise to the nucleus of P. falciparum in ring-, trophozoite- and schizont-stages in the IDC. Bound antibody shown in green in the first row was specific for the histone modifications indicated at the bottom of the figure. DNA was stained blue with DAPI in the second row. Bright field microscopy shows the cell morphology in the fourth row. Scale bar is 5 μm.

Tang J, Chisholm SA, Yeoh LM, Gilson PR, Papenfuss AT, Day KP, Petter M, Duffy MF. Histone modifications associated with gene expression and genome accessibility are dynamically enriched at Plasmodium falciparum regulatory sequences. Epigenetics Chromatin. 2020 13(1):50.