PF3D7_1360800 falcilysin

Clone MP3 parasites were observed live by epifluorescence microscopy. (i) During the ring stage, FLN is distributed diffusely in the cytosol and persists there throughout the entire cycle. (ii) As rings develop into trophozoites, FLN is concentrated into an intense fluorescent focus. (iii) During the schizont stage, the intense focus appears to elongate and divide. (iv) One intense focus per merozoite is observed in segmenters. Subcellular localization indicates association with the apicoplast.

Ponpuak M, Klemba M, Park M, Gluzman IY, Lamppa GK, Goldberg DE. A role for falcilysin in transit peptide degradation in the Plasmodium falciparum apicoplast. Mol Microbiol. 2007 63:314-34

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