Immunolabeling of Plasmodium falciparum isolate FC27 with anti-Ag617 and protein A-4 nm gold. Bars equal 0.1 mm. (A, B, and D) Erythrocyte surface of trophozoite infected cells showing labeling under knobby erythrocyte plasma membrane. (C) Surface of a schizont infected cell with labeling of knobs and odd gold particles over parasitophorous vacuole, erythrocyte cytoplasm, and parasite. (E) Knobby surface of schizont infected cell incubated without antisera, only protein A-4 nm gold, showing no gold associated with plasma membrane.

Culvenor JG, Langford CJ, Crewther PE, Saint RB, Coppel RL, Kemp DJ, Anders RF, Brown GV. Plasmodium falciparum: identification and localization of a knob protein antigen expressed by a cDNA clone. Exp Parasitol. 1987 63:58-67. Copyright Elsevier 2010.